Decrease (-) Restore Default Increase (+)
Print    Email
Font Size Print Email
Bookmark and Share
left
right
cap_wrapper_header
cap_wrapper_left
Our Locations
Health Library
Body Guide
Care Guides
Health Risk Assessments
My Checkups
DecisionAssist
Thomson Drug Interaction Checker
Thomson Drug Notes
Wellness Tools
Health Centers
Health Library (En Espanol)
spacer

Health Library

Search Health Information   
 

MIBG scintiscan

Definition

An MIBG scintiscan is an imaging test that uses a radioactive substance (called a tracer) and a special scanner to find or confirm the presence of pheochromocytoma and neuroblastoma, which are tumors of specific types of nervous tissue.

See also: Nuclear scan

Alternative Names

Adrenal medullary imaging; Meta-iodobenzylguanidine scintiscan

How the test is performed

A radioisotope (MIBG, iodine-131-meta-iodobenzylguanidine) is injected into a vein. This compound attaches to specific tumor cells.

Later that day (or the next day) you lie on a table that is positioned under the arm of the scanner. The abdomen is scanned. You may be asked to return for repeated scans for 1 - 3 days. Each scan takes 1 - 2 hours.

Before or during the test, you may be given an iodine solution to prevent the thyroid from absorbing too much of the radioisotope.

How to prepare for the test

You must sign an informed consent form. You will be asked to wear a hospital gown. However, loose-fitting clothing may be allowed. Remove jewelry or metal objects before each scan.

How the test will feel

There is a sharp needle prick when the material is injected. The table may be cold or hard. You must lie still during the scan.

Why the test is performed

This test is done to confirm pheochromocytoma or neuroblastoma.

Normal Values

There are no signs of a tumor.

What abnormal results mean

Most often, this test is used to locate pheochromocytoma. It may be very useful to detect multiple tumors or tumors that are located outside the adrenal tissues.

Additional conditions under which the test may be performed include multiple endocrine neoplasia (MEN) II

What the risks are

There is some exposure to radiation from the radioisotope. Because the radiation from this radioisotope is fairly high compared to most others, some precautions may be necessary for a few days after the test. Your health care provider will tell you about specific precautions, which may include flushing the toilet twice after each use (to dilute radioactive material excreted in the urine).

Before or during the test, you may be given an iodine solution to prevent excess iodine from being absorbed into the thyroid.

This test should NOT be done on pregnant women because of the danger to the fetus from radiation.

Special considerations

The radioisotope is costly and may not be available in all medical facilities.

Because the radiation from this radioisotope is fairly high compared to most other radioisotopes, some precautions may be necessary for a few days after the test.

Your health care provider will tell you about specific precautions, which may include flushing the toilet twice after each use (to dilute any radioactive material that passed out through the urine).

References

Aslam S, Sohaib A, Rockall A, Bomanji JB, Evanson J, Roznek RH. Imaging of the endocrine system. In: Adam A, Dixon AK, eds. Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging. 5th ed. New York, NY: Churchill Livingstone; 2008:chap 71.

Segerman D, Miles KA. Radionuclide imaging: general principles. In: Adam A, Dixon AK, eds. Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging. 5th ed. New York, NY: Churchill Livingstone; 2008:chap 7.

Young WF. Adrenal medulla, catecholamines, and pheochromocytoma. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 246.


Review Date: 11/21/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com
 

Who We Are

Contact & Connect

Hospitals & Locations

Health Education & Tools

cap_wrapper_right
cap_wrapper_footer